Hematological and blood chemical changes of rabbits infected with rabbit hemorrhagic disease virus were studied and the results were summarized as follows:
l. Total leukocyte count (2,410±1,076/㎕), lymphocyte count (1,582±632.5㎕) and heterophil count (705±411.1㎕) were significantly decreased after 24 hours of the infection (p<0.01). However, no significant changes were observed in monocyte, eosinophil and basophil numbers.
2. A significant increase of aspartate aminotransferase (96IU/L), alanine aminotransferase (96IU/L) and alkaline phosphatase (401.1±131.8IU/L) was observed (p<0.01).
3. A moderate increase of BUN (26.9±3.6㎎/100㎖) and creatinine (3,2±1.9㎎/100㎖) was observed (p<0.05).
4. No significant changes of r-GTP, thymol turbidity, glucose, cholesterol, albumin, total serum protein, fibrinogen were observed.
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